Diffuse b cell nhl. Indolent lymphomas are slow moving and tend to grow more slowly and have fewer signs and symptoms when first diagnosed. Burkitt lymphoma may spread to the central nervous system cns. Burkitt lymphoma is a rare but highly aggressive fast growing b cell non hodgkin lymphoma nhl.
Dlbcl can arise in virtually any part of the body and. Diffuse large bcell lymphoma dlbcl is the most common type of nonhodgkin lymphoma nhl in the united states representing approximately 24 of new cases of nhl each year. Diffuse large b cell lymphoma is a cancer of b cells a type of lymphocyte that is responsible for producing antibodies.
The most common type of nhl is diffuse large b cell lymphoma not otherwise specified dlbcl nos accounting for 30 of all nhl cases. Dlbcl is an aggressive fast growing nhl that affects b lymphocytes. Diffuse large b cell lymphoma is a non hodgkins lymphoma nhl.
Dlbcl can affect people of any age but it occurs mostly in older people. More than 18000 people are diagnosed with dlbcl each year. Slow growing or indolent subtypes represent about 40 percent of all nhl cases.
This regimen known as r chop is most often given in cycles 3 weeks apart. 1 2 the disease is aggressive and patients typically present with rapidly enlarging lymphadenopathy and constitutional symptoms necessitating immediate treatment. Non hodgkin lymphoma nhl is one of the most frequently diagnosed cancer types representing approximately 4 of cancers worldwide.
Out of over 60 types of nhls diffuse large b cell lymphoma is the most common. Diffuse large b cell lymphoma dlbcl is the most common type of non hodgkin lymphoma nhl in the united states and worldwide accounting for about 22 percent of newly diagnosed cases of b cell nhl in the united states. It is the most common form of non hodgkin lymphoma among adults with an annual incidence of 78 cases per 100000 people per year in the us and uk.
The lymphoma cells look fairly large when seen with a microscope. Follicular lymphoma fl is the most common subtype of indolent nhl. Diffuse large b cell lymphoma dlbcl is the most common aggressive nhl subtype.
Dlbcl is the most aggressive or fast growing form of. Diffuse large b cell lymphoma dlbcl this is the most common type of nhl in the united states accounting for about 1 out of every 3 lymphomas.